Question: Pick Three Conditions From Each Of The High And Low Groups And Give A Physiological Explanation For Why That Condition Would Affect Hct/Hgb As It Does. For Example: EPO (erythropoietin) Is Listed Under High Hemoglobin. Why? The Body Detects Low Oxygen Levels In The Blood Through Signaling Pathways In The Kidney. The Kidney Does Not Know Why Oxygen Is …

Pick three conditions from each of the high and low groups andgive a physiological explanation for why thatcondition would affect Hct/Hgb as it does.

For example: EPO (erythropoietin) is listedunder high hemoglobin. Why? The body detects low oxygen levels inthe blood through signaling pathways in the kidney. The kidney doesnot know why oxygen is low, only that it is. The response is torelease EPO from the endocrine cells in the kidney. The EPO travelsthrough the blood stream to the bone marrow, where it stimulateshemopoietic stem cells to mature developing into red blood cells.These cells get released into the blood stream, allowing for moreoxygen to be transported, which shuts down the feedback cycle thatwas started in the kidney from low oxygen.

High Hct:

1. Severe burns

2. Dehydration

3. Diarrhea

Low Hct:

4. Pregnancy

5. Cancer

6. Iron Deficiency

High Hgb:

7. Smoking

8. COPD

9. Emphysema

Low Hgb:

10. Acute or Chronic Bleeding

11. Chemotherapy

12. Autoimmune Diseases