Question: 13. (3 Pts) Two Proteins Are Detected In The Endomembrane System. One, Collagen, Is Destined For Secretion From The Cell, And The Other, Lysozyme, Is Destined To Go To A Lysosome. How Does The Cell “know” Where Each Protein Should Go, And How Does This Sorting Process Occur? 14. Lysosomes Must Have An Acidic PH So That Digestive Enzymes Function Optimally….

13. (3 pts) Two proteins are detected in the endomembrane system. One, collagen, is destined for secretion from the cell, and the other, lysozyme, is destined to go to a lysosome. How does the cell “know” where each protein should go, and how does this sorting process occur? 14. Lysosomes must have an acidic pH so that digestive enzymes function optimally. How does the lysosome become acidic? A. P-type ATPase pumps protons into lysosome B. V-type ATPase pumps protons into lysosome C. ABC-type ATPase pumps protons into lysosome D. Porins channel acidic compounds into the lysosome. E. nuclear pore 15. (8 pts) Matching: match each word to the phrase that best describes it. (Not all words will be used. None should be used more than once.) A. clathrin I. retrograde B. endosome F. exportin J. nucleoporins C. Ran-GTP G. lamin K. caveolin D. SNARES H. endocytosis L. perinuclear space Movement of vesicles from the Golgi to the endoplasmic reticulum. Protein receptors that help vesicles fuse with their target membrane. Protein that lines the inner surface of the nuclear envelope. Protein that coats the outer surface of vesicles moving from the trans-Golgi to endosomes. Protein that causes the release of cargo that has entered through the nuclear pore. Proteins that form the parts of the nuclear pore. Compartment that will mature to form a lysosome. The region between the membranes of the nuclear envelope is called this. Binding of ligands to cell surface receptors can initiate the formation of vesicles via this process. This protein recognizes large molecules destined to move from the nucleus to the cytoplasm.